truB

truB
168

tRNA pseudouridine 55 synthase

locus
BSU_16660
Molecular weight
34.05 kDa
pI
6.65
Protein length
Gene length
function
tRNA modification
product
tRNA pseudouridine 55 synthase
essential
no
synonyms
truB, ylxN, ymxF

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0130 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,736,886  1,737,815
The protein
Catalyzed reaction/ biological activity
uridine55 in tRNA --> pseudouridine55 in tRNA (according to UniProt)
Protein family
pseudouridine synthase TruB family (single member, according to UniProt)
Structure
[PDB|1ZE1] (from Thermotoga maritima, 36% identity) [pubmed|14990747]
[AF|P32732]
Biological materials
Mutant
BKE16660 ([gene|425FC9847D10A6FA9725D6523CD3213C57B371BE|truB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16660 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGCCTTTCACTCCTTC,  downstream forward: _UP4_CAATAGAAAAAAGGTGACCG
BKK16660 ([gene|425FC9847D10A6FA9725D6523CD3213C57B371BE|truB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16660 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGCCTTTCACTCCTTC,  downstream forward: _UP4_CAATAGAAAAAAGGTGACCG
References
24371284,7489483,14990747

425FC9847D10A6FA9725D6523CD3213C57B371BE

Page visits: 1418

Time of last update: 2024-10-11 19:29:50

Author of last update: Jstuelk