spoVV
168
transporter for dipicolinic acid across the outer forespore membrane
locus
BSU_15030
Molecular weight
44.68 kDa
pI
10.27
function
transport of dipicolinic acid across the outer forespore membrane
product
dipicolinic acid transporter
essential
no
synonyms
spoVV, ylbJ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3314 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,570,574 1,571,800
Phenotypes of a mutant
inactivation of ''[gene|40BCEB3648585961D22B71BBB4FB62EE4B3E360D|spoVV]'' eliminates [wiki|sporulation] [Pubmed|26735940], this can be suppressed by inactivation of the genes of the [gene|EEDE6A22E91992ABCA677CAB7917B7168C5CB868|gerAA]-[gene|5FF739B8C087207039BB6DC293EE77F59337ED0B|gerAB]-[gene|D937E26DF69D49B1341B37596AC6A8FBEEF8BA2E|gerAC] operon [pubmed|28605069]
The protein
Catalyzed reaction/ biological activity
transport of dipicolinic acid across the outer forespore membrane [pubmed|28945739]
Structure
[AF|O34765]
[wiki|Localization]
outer forespore membrane [pubmed|28945739]
Expression and Regulation
Operons
genes
[gene|40BCEB3648585961D22B71BBB4FB62EE4B3E360D|spoVV]
description
[Pubmed|22383849]
regulation
expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]) [Pubmed|12662922,15699190]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, [Pubmed|15383836], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|12662922,15699190], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-B246 (ylbJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1245 NBRP B. subtilis, Japan]
BKE15030 ([gene|40BCEB3648585961D22B71BBB4FB62EE4B3E360D|spoVV]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTTACCTCCCCGATGC, downstream forward: _UP4_ACAAAAAAAGGATGAGTCAA
BKK15030 ([gene|40BCEB3648585961D22B71BBB4FB62EE4B3E360D|spoVV]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTTACCTCCCCGATGC, downstream forward: _UP4_ACAAAAAAAGGATGAGTCAA
References
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Time of last update: 2024-12-21 19:43:28
Author of last update: Jstuelk