yonN
168
SP prophage-derived DNA-binding protein HU 2
locus
BSU_21050
Molecular weight
9.71 kDa
pI
10.23
function
untwisting of the DNA double helix
product
DNA-binding protein HU 2
essential
no
synonyms
yonN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0776 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,225,337 2,225,615
The protein
Catalyzed reaction/ biological activity
[protein|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]-mediated untwisting of the DNA stimulates [protein|C352560155F5B2E951B5059794D7B319C1A3AF2C|nth] endonuclease activity at AP sites [Pubmed|21954439]
Protein family
bacterial histone-like protein family (with [protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|hbs], according to UniProt)
Structure
[PDB|1HUE] ([protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|hbs] from B. stearothermophilus, 71% identity) [pubmed|7500343]
[AF|P68573]
Paralogous protein(s)
[protein|EFD8FC875B6787B1512C5FC4C81E7E4C9BD93028|hbs]
Expression and Regulation
Operons
genes
[gene|121C3C9CF49711316A526B9571F020BE8E304B31|yonP]-[gene|34380A2F469ACFD90D450717A41D6F5CC19DCD7E|yonO]-[gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]
description
[pubmed|22383849]
Biological materials
Mutant
BKE21050 ([gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE21050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATCAATTTCCTCCTAA, downstream forward: _UP4_TAATCAGTTAATGAGGACGA
BKK21050 ([gene|3FFFA28E2C16508C6A94408B739864DB7F8DD1F7|yonN]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK21050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATCAATTTCCTCCTAA, downstream forward: _UP4_TAATCAGTTAATGAGGACGA
References
Page visits: 2227
Time of last update: 2024-10-10 08:21:46
Author of last update: Melvin.boenninger