sdpI
168
immunity protein, protection against SdpC
locus
BSU_33780
Molecular weight
23.15 kDa
pI
9.61
function
protection against SdpC
product
immunity protein
essential
no
ec
null
synonyms
sdpI, yvaZ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5658 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,466,434 3,467,057
The protein
Structure
[AF|O32241]
Effectors of protein activity
in the presence of extracellular [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC], [protein|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI] binds and sequesters [protein|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR] , this results in induction of the ''[gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]-[gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]'' operon [Pubmed|16469701]
Paralogous protein(s)
[protein|2B7F65B145005A8ADD2A278E3EA5A52DF162C837|yfhL], [protein|2E0FBCA66FB88EDFD345FA289F776C7CA23976F5|ybgB]
[wiki|Localization]
membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]-[gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]
description
[Pubmed|12817086]
regulation
induced by extracellular [protein|search|SdpC] ([protein|search|SdpR]) [Pubmed|16469701]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|16469701], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
[protein|29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR]: repression, [Pubmed|16469701], in [regulon|protein:29A3EC8FB0C763A973273AA14EAEB904847C3002|sdpR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16469701], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A454 (yvaZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/454 NBRP B. subtilis, Japan]
BKE33780 ([gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATTATGGAAATTATATTTT, downstream forward: _UP4_TGAAAAAGTGTCTTGCGGAG
BKK33780 ([gene|3FB5839A7A80CF52E627FF1744E50490F5CC390F|sdpI]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATTATGGAAATTATATTTT, downstream forward: _UP4_TGAAAAAGTGTCTTGCGGAG
References
Reviews
Original Publications
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Time of last update: 2024-12-19 18:11:39
Author of last update: Melvin.boenninger