queG
168
epoxyqueuosine reductase
locus
BSU_08910
Molecular weight
48.37 kDa
pI
7.35
function
synthesis of queuosine, tRNA modification
product
epoxyqueuosine reductase
essential
no
synonyms
queG, ygaP, yhbA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1600 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
967,935 969,095
The protein
Catalyzed reaction/ biological activity
conversion of epoxyqueuosine to queuosine [Pubmed|21502530]
AH2 + epoxyqueuosine34 in tRNA = A + H2O + queuosine34 in tRNA (according to UniProt)
Protein family
QueG family (single member, according to UniProt)
[wiki|Domains]
[wiki|4Fe-4S ferredoxin-type domain] (aa 178-208) (according to UniProt)
[wiki|Cofactors]
cobalamin
Fe-S cluster [Pubmed|21502530]
Structure
[PDB|5D08] [Pubmed|27638883]
[AF|P97030]
Expression and Regulation
Operons
genes
[gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A241 (yhbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/241 NBRP B. subtilis, Japan]
BKE08910 ([gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTGCACAGCCTCCT, downstream forward: _UP4_TGACATACGTATAGAGCAGA
BKK08910 ([gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTGCACAGCCTCCT, downstream forward: _UP4_TGACATACGTATAGAGCAGA
References
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Time of last update: 2024-09-16 19:02:07
Author of last update: Melvin.boenninger