spoVFA

spoVFA
168

dipicolinate synthase (subunit A)

locus
BSU_16730
Molecular weight
31.80 kDa
pI
5.89
Protein length
Gene length
function
dipicolic acid production
product
dipicolinate synthase (subunit A)
essential
no
ec
null
synonyms
spoVFA, dpaA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5842 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,744,367  1,745,260
The protein
Catalyzed reaction/ biological activity
(S)-2,3-dihydrodipicolinate + NADP+ --> dipicolinate + H+ + NADPH (according to UniProt)
Structure
[PDB|2RIR]
[AF|Q04809]
Expression and Regulation
Operons
genes
[gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]-[gene|4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8|spoVFB]-[gene|564A2F43F8AABE97FC8F0B1B3382A9F31F02FA18|asd]-[gene|6D6718AC72C9D86EDE16B191EDAB3ABA488B689B|dapG]-[gene|00B4CA4E25858A56F9D4E0ADEE2643F203FEC613|dapA]
description
[Pubmed|8098035]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190,8098035]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,8098035], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]→[gene|00B4CA4E25858A56F9D4E0ADEE2643F203FEC613|dapA]

2024-10-09 15:33:25

ghost

97

9f1758bf801d23548827e9d03f6ca9d0c2e6746d

C373CB045AB9232B86B60761B90C3510E98A06A8

Biological materials
Mutant
BKE16730 ([gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTAAACGTTCACCTTC,  downstream forward: _UP4_CAAGCTGAGGAGGGGAAATA
BKK16730 ([gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTAAACGTTCACCTTC,  downstream forward: _UP4_CAAGCTGAGGAGGGGAAATA
References
8345520,8098035,15699190,35638784

3DA80060554B78E9DC2189CECB78680095B08B32

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Time of last update: 2024-10-11 19:34:59

Author of last update: Jstuelk