Explore the novel features of the upcoming release of in its beta version,
SubtiWiki v5! It features genomic conservation, interaction of proteins with metabolites, dedicated metabolite pages, and much more!
Check the pages for
MntR and
manganese!
yukD
168
Ubiquitin-like protein, part of the type VII protein secretion system [protein|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]-[protein|3FE4A91C7D0B43C8704391F2F9493852B3AED9B0|essB]-[protein|6007664F3D979B4D8D4662C7F6E5CF2F489268E3|yukB]-[protein|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]-[protein|DA52C4CD130F32734E01A52F2F395127D2260F61|yueC], putative bacteriocin
function
export of [protein|A177DF098115F85F23A1D42EFB07D294B515830F|yfjA], [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE], [protein|75B0239578C92D4F3B298CBB077635BF5567C590|yxiB], [protein|2401A4E3E5E683472C51AB2F31BC4F54F672F32A|ywqH]
product
ubiquitin-like protein, part of the type VII protein secretion system, putative bacteriocin
Genomic Context
This gene is a member of the following
regulons
Gene
Coordinates
3,275,832 3,276,071
Phenotypes of a mutant
loss of secretion of [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE] [Pubmed|24798022]
The protein
Catalyzed reaction/ biological activity
export of [protein|A177DF098115F85F23A1D42EFB07D294B515830F|yfjA], [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE], [protein|75B0239578C92D4F3B298CBB077635BF5567C590|yxiB], [protein|2401A4E3E5E683472C51AB2F31BC4F54F672F32A|ywqH] [Pubmed|39436054,24828531,23861817,11973144]
secretion and delivery of [wiki|LXG domain] toxins [pubmed|34280190]
Protein family
EsaB family (single member, according to UniProt)
Structure
Expression and Regulation
Operons
genes
[gene|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]-[gene|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]-[gene|3FE4A91C7D0B43C8704391F2F9493852B3AED9B0|essB]-[gene|6007664F3D979B4D8D4662C7F6E5CF2F489268E3|yukB]-[gene|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]-[gene|DA52C4CD130F32734E01A52F2F395127D2260F61|yueC]-[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
description
[Pubmed|22383849]
regulation
expressed in the stationary phase [Pubmed|23861817]
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
regulatory mechanism
[protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]-P, [Pubmed|23861817], in [regulon|protein:D343D2096664A972026D911E7A17A35C7B1CD1C9|degU regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|22383849], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[gene|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]→[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
2025-02-01 00:14:53
Jstuelk
126
BB0E1B9684F16E121BAA022EF986B0285FB41FA7
CDC40F8A7006CF56CF9A6155897E8BD27FFEC7AA
Biological materials
Mutant
MGNA-A627 (yukD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/627 NBRP B. subtilis, Japan]
BKE31900 ([gene|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTAGGATCACCCTTACA, downstream forward: _UP4_ATATTATGAAAGGATCTGGT
BKK31900 ([gene|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTAGGATCACCCTTACA, downstream forward: _UP4_ATATTATGAAAGGATCTGGT
References
Reviews
19155186,11973144,38957458 Original Publications
15576783,16845009,22383849,23861817,15978580,24798022,34280190,36154281,39436054
