yveA
168
similar to aspartate/ glutamate transporter
locus
BSU_34470
Molecular weight
56.82 kDa
pI
9.68
function
unknown
product
similar to aspartate/ glutamate transporter
essential
no
synonyms
yveA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0531 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,539,165 3,540,727
The protein
Protein family
[wiki|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)
Structure
[PDB|5OQT] (YneM from E. coli, 28% identity) [pubmed|29416041]
[AF|O07002]
Paralogous protein(s)
[protein|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]
[wiki|Localization]
cell membrane (according to UniProt)
Additional information
the protein has been annotated as aspartate transporter. It is, however, not implicated in aspartate uptake in exponentially growing cells [Pubmed|25344233]
Expression and Regulation
Operons
genes
[gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]
description
[Pubmed|16497325]
regulation
expressed during sporulation in the forespore ([protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]) [Pubmed|16497325]
regulatory mechanism
[protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]-P, [Pubmed|2428811], in [regulon|protein:D343D2096664A972026D911E7A17A35C7B1CD1C9|degU regulon]
sigma factors
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|16497325], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
Biological materials
Mutant
GP2385 ∆[gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::''cat'', available in [wiki|Jörg Stülke]'s lab
GP2795 ∆[gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::''spec'', available in [wiki|Jörg Stülke]'s lab
GP2822 ∆[gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::''neo'', available in [wiki|Jörg Stülke]'s lab
GP4154 (Δ[gene|533EEB1A454D29800C9A00A0BE107ECEE2138DAB|gltT]::''kan'') (Δ[gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::''cat''), available in [wiki|Jörg Stülke]'s lab
BKE34470 ([gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGCTTCCTCCTTTGAA, downstream forward: _UP4_TAAAGAAGCAAGAGGTTTTC
BKK34470 ([gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCGCTTCCTCCTTTGAA, downstream forward: _UP4_TAAAGAAGCAAGAGGTTTTC
MDB43 ([gene|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|yveA]::neo trpC2 pheA1 available in [wiki|Erhard Bremer]'s and [wiki|Jörg Stülke]'s labs [Pubmed|25344233]
MGNA-B615 (yveA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1614 NBRP B. subtilis, Japan]
References
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Time of last update: 2024-10-12 11:11:55
Author of last update: Jstuelk