glgP
168
glycogen phosphorylase
locus
BSU_30940
Molecular weight
91.56 kDa
pI
6.28
function
glycogen biosynthesis
product
glycogen phosphorylase
essential
no
ec
2.4.1.1
synonyms
glgP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0058 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,163,735 → 3,166,131
The protein
Catalyzed reaction/ biological activity
[(1→4)-α-D-glucosyl](n) + phosphate --> [(1→4)-α-D-glucosyl](n-1) + α-D-glucose 1-phosphate (according to UniProt)
Protein family
glycogen phosphorylase family (single member, according to UniProt)
[wiki|Cofactors]
PLP (according to UniProt)
Structure
[PDB|1PYG] (from Oryctolagus cuniculus, 45% identity) [pubmed|1962195]
[AF|P39123]
Modification
phosphorylation on (Thr-291 OR Ser-294) [Pubmed|17218307]
Expression and Regulation
Operons
genes
[gene|52C8DE3C78B680C8883D1CD559CBC2D9ABFCC400|glgB]-[gene|B665735B76462724A3C7A1E89D3E613C18F21399|glgC]-[gene|63A4FD35A2E72C665BFA3F2632F06C7A0C954087|glgD]-[gene|EBEA85AD543B79C321CB5F28D1B7E1248640DC1D|glgA]-[gene|3AB4513126EFF54996A54CB7DEB6062C1A06AAC3|glgP]
description
[Pubmed|8145641]
regulation
expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|8145641]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|8145641], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
BKE30940 (Δ[gene|3AB4513126EFF54996A54CB7DEB6062C1A06AAC3|glgP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAAAAATAAGTCTGCAAAGC, downstream forward: _UP4_TGAAAAAGCCGCTGTATAAG
BKK30940 (Δ[gene|3AB4513126EFF54996A54CB7DEB6062C1A06AAC3|glgP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAAAAATAAGTCTGCAAAGC, downstream forward: _UP4_TGAAAAAGCCGCTGTATAAG
References
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Time of last update: 2024-10-10 16:19:13
Author of last update: Melvin.boenninger