glyS
168
glycyl-tRNA synthetase (beta subunit)
locus
BSU_25260
Molecular weight
76.05 kDa
pI
4.97
function
translation
product
glycyl-tRNA synthetase (beta subunit)
essential
yes
ec
6.1.1.14
synonyms
glyS, yqfK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0751 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,605,730 2,607,769
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
ATP + glycine + tRNAGly --> AMP + diphosphate + glycyl-tRNAGly (according to UniProt)
Protein family
[wiki|Class-II aminoacyl-tRNA synthetase family] (according to UniProt)
Structure
[PDB|1J5W] (from ''Thermotoga maritima'', 55% identity, 72% similarity)
[AF|P54381]
Expression and Regulation
Operons
genes
[gene|FD84CF3E05B81BD38D8C8FF5B04728FB3912D9B5|glyQ]-[gene|337BF226112A48C39A24E6D5C7A63F864502914C|glyS]
description
[Pubmed|22383849]
regulation
induced by glycine limitation ([protein|search|T-box]) [Pubmed|19258532,28531275]
regulatory mechanism
T-box: RNA switch, [Pubmed|19258532,28531275], in [regulon|other_regulator:T-box|T-box]
References
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Time of last update: 2025-01-28 08:56:35
Author of last update: Jstuelk