lnrL

lnrL
168

similar to ABC transporter (ATP-binding protein), involved in resistance to linearmycin

Locus
BSU_08310
Molecular weight
33.95 kDa
Isoelectric point
6.5
Protein length
311 aaSequenceBlast
Gene length
936 bpSequenceBlast
Function
resistance to linearmycin
Product
ABC transporter (ATP-binding protein)
Essential
no
Synonyms
yfiL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1131 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
905,816  906,751
The protein
Protein family
ABC transporter superfamily (according to UniProt)
Domains
ABC transporter domain (aa 2-232) (according to UniProt)
Structure
4YER (PDB) (from Thermotoga maritima, 39% identity)
P94440 (AlphaFold)
Localization
membrane associated (via LnrM-LnrN) PubMed
Expression and Regulation
Operons
Genes
lnrL-lnrM-lnrN
Description
PubMed
Regulation
expression during spore germination is increased under conditions of osmotic stress PubMed
induced in the presence of linearmycin and other polyenes (LnrK) PubMed
Regulatory mechanism
LnrK: activation, PubMed, in lnrK regulon
Sigma factors
SigF: sigma factor, in sigF regulon
SigG: sigma factor, in sigG regulon
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lnrL→lnrN

2025-03-07 04:44:44

Jstuelk

73

7fa1f47baf646398b2d2b81a08036e691ef5d550

3B045C04B4C45662F4875ADEB7A4D524530CAE31

Biological materials
Mutant
MGNA-C354 (yfiL::erm), available at the NBRP B. subtilis, Japan
BKE08310 (lnrL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACGTCGTCTCACTCCTTTT,  downstream forward: _UP4_TTGCGGGATTGAGGAGGGAC
BKK08310 (lnrL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACGTCGTCTCACTCCTTTT,  downstream forward: _UP4_TTGCGGGATTGAGGAGGGAC
References
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329E4DF9EF1545AABE485B9BBCD22F09ABF019A1

Page visits: 4813

Time of last update: 2025-04-27 08:43:27

Author of last update: Jstuelk