deoD
168
purine nucleoside phosphorylase
locus
BSU_19630
Molecular weight
25.23 kDa
pI
4.98
function
purine salvage and interconversion
product
purine nucleoside phosphorylase
essential
no
ec
2.4.2.1
synonyms
deoD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0813 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,135,470 2,136,171
The protein
Catalyzed reaction/ biological activity
purine D-ribonucleoside + phosphate --> purine nucleobase + α-D-ribose 1-phosphate (according to UniProt)
purine 2'-deoxy-D-ribonucleoside + phosphate --> 2-deoxy-α-D-ribose 1-phosphate + purine nucleobase (according to UniProt)
Protein family
PNP/UDP phosphorylase family (with [protein|5B21D1E73A65B13CE4DDA32ABC71EFA54E8D1D8F|mtnN], according to UniProt)
Structure
[PDB|4D8V] [Pubmed|22957058]
[AF|O34925]
Expression and Regulation
Operons
genes
[gene|3075327DBE55C4F628171AEE248CAED5870693FA|deoD]-[gene|9A22825FD67B6A205807433D0B4908F86E5AB343|ldcB]
description
[Pubmed|22383849]
Biological materials
Mutant
BKE19630 ([gene|3075327DBE55C4F628171AEE248CAED5870693FA|deoD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCATATCCTCCTGTAA, downstream forward: _UP4_TAAAATATATCAAGAGGCGT
BKK19630 ([gene|3075327DBE55C4F628171AEE248CAED5870693FA|deoD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCATATCCTCCTGTAA, downstream forward: _UP4_TAAAATATATCAAGAGGCGT
References
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Time of last update: 2024-10-04 04:06:21
Author of last update: Melvin.boenninger