fluC

fluC
168

flouride exporter (together with [protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV])

locus
BSU_09600
Molecular weight
12.31 kDa
pI
9.85
Protein length
Gene length
function
export of flouride
product
flouride channel
essential
no
synonyms
fluC, yhdU, crcBA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0239 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,036,953  1,037,309
Phenotypes of a mutant
very sensitive to flouride [pubmed|30430725]
The protein
Protein family
CrcB (TC 9.B.71) family, (together with [protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV], according to UniProt)
Structure
[PDB|5A40] (from Bordetella pertussis, 41% identity, aa 7 ... 87) [pubmed|26344196]
[AF|O07590]
Paralogous protein(s)
[protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|04CACAF4F786090AB67D7C606C944F07B7A7FE55|yhdW]-[gene|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV]-[gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]
description
[Pubmed|22383849]
Open in new tab

[gene|04CACAF4F786090AB67D7C606C944F07B7A7FE55|yhdW]→[gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]

2024-09-28 20:25:16

Jstuelk

58

e949606f7fb4fef10336881f989750325fd2e9fd

9315E1988E88DBCB0E6AA1EDB2B69897632E0447

Biological materials
Mutant
MGNA-B486 (yhdU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1485 NBRP B. subtilis, Japan]
BKE09600 ([gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCCTATGAAAATACCCGCTA,  downstream forward: _UP4_ATCACAATATAAAAAAACCT
BKK09600 ([gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09600 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CCCTATGAAAATACCCGCTA,  downstream forward: _UP4_ATCACAATATAAAAAAACCT
References
Reviews
28514705
Research papers
26344196,23991286,30430725,36815589

2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED

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Time of last update: 2024-10-07 03:20:41

Author of last update: Jstuelk