fluC
168
flouride exporter (together with [protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV])
locus
BSU_09600
Molecular weight
12.31 kDa
pI
9.85
function
export of flouride
product
flouride channel
essential
no
synonyms
fluC, yhdU, crcBA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0239 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,036,953 1,037,309
Phenotypes of a mutant
very sensitive to flouride [pubmed|30430725]
The protein
Protein family
CrcB (TC 9.B.71) family, (together with [protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV], according to UniProt)
Structure
[PDB|5A40] (from Bordetella pertussis, 41% identity, aa 7 ... 87) [pubmed|26344196]
[AF|O07590]
Paralogous protein(s)
[protein|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|04CACAF4F786090AB67D7C606C944F07B7A7FE55|yhdW]-[gene|BD1C4D9E6E8960DF77EE1571A637929C2D8C4A28|yhdV]-[gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B486 (yhdU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1485 NBRP B. subtilis, Japan]
BKE09600 ([gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCCTATGAAAATACCCGCTA, downstream forward: _UP4_ATCACAATATAAAAAAACCT
BKK09600 ([gene|2F86A2FF36ED00DB0A9A91B064EBD095F5E759ED|fluC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCCTATGAAAATACCCGCTA, downstream forward: _UP4_ATCACAATATAAAAAAACCT
References
Reviews
Research papers
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Time of last update: 2024-12-20 17:26:53
Author of last update: Jstuelk