ylaG

ylaG
168

similar to GTP-binding elongation factor

locus
BSU_14770
Molecular weight
68.21 kDa
pI
4.97
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
ylaG, bipA, typA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1217 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,546,121  1,547,959
The protein
Catalyzed reaction/ biological activity
in E. coli, the corresponding protein (BipA) incorporates ribosomal protein [protein|20485A785D3AF82889F2018D3EA5B5FA33E64E95|L6] into the nascent large ribosomal subunit [pubmed|30305394]
Protein family
[wiki|TRAFAC class translation factor GTPase superfamily] (according to UniProt)
[wiki|Classic translation factor GTPase family] (according to UniProt)
[wiki|Domains]
[wiki|tr-type G domain] (aa 5-200) (according to UniProt)
Structure
[PDB|4ZCM] (from E. coli, 55% identity) [pubmed|26163516]
[AF|O07631]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]-[gene|8DE3D48909BDBD2091432047E79063E9EEE63115|ylaH]
description
[pubmed|22383849]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
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[gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]->[gene|8DE3D48909BDBD2091432047E79063E9EEE63115|ylaH]

2024-11-23 17:48:10

Bzhu

64

ebee84da774a79804c2a59676843f993dfae81f0

B7F12C431B6D7CF0EE4A2F50A902644B786A73EE

Biological materials
Mutant
MGNA-A536 (ylaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/536 NBRP B. subtilis, Japan]
BKE14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA,  downstream forward: _UP4_TAATCTCGTGCAGAATTTGA
BKK14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14770 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA,  downstream forward: _UP4_TAATCTCGTGCAGAATTTGA
References
36815589,36815589,11948165,12399512,30305394,26163516

2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3

Page visits: 3632

Time of last update: 2024-12-05 09:52:42

Author of last update: Jstuelk