ylaG
168
similar to GTP-binding elongation factor
locus
BSU_14770
Molecular weight
68.21 kDa
pI
4.97
function
unknown
product
unknown
essential
no
synonyms
ylaG, bipA, typA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1217 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,546,121 1,547,959
The protein
Catalyzed reaction/ biological activity
in E. coli, the corresponding protein (BipA) incorporates ribosomal protein [protein|20485A785D3AF82889F2018D3EA5B5FA33E64E95|L6] into the nascent large ribosomal subunit [pubmed|30305394]
Protein family
[wiki|TRAFAC class translation factor GTPase superfamily] (according to UniProt)
[wiki|Classic translation factor GTPase family] (according to UniProt)
[wiki|Domains]
[wiki|tr-type G domain] (aa 5-200) (according to UniProt)
Structure
[PDB|4ZCM] (from E. coli, 55% identity) [pubmed|26163516]
[AF|O07631]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]-[gene|8DE3D48909BDBD2091432047E79063E9EEE63115|ylaH]
description
[pubmed|22383849]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
Biological materials
Mutant
MGNA-A536 (ylaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/536 NBRP B. subtilis, Japan]
BKE14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA, downstream forward: _UP4_TAATCTCGTGCAGAATTTGA
BKK14770 ([gene|2D0A95A37214E9BF58E2DE732DE9F32AAF9C1CD3|ylaG]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTTTTCATCTCCTAAAA, downstream forward: _UP4_TAATCTCGTGCAGAATTTGA
References
Page visits: 3648
Time of last update: 2024-12-21 04:37:01
Author of last update: Jstuelk