yqgS
168
polyglycerolphosphate lipoteichoic acid synthase
locus
BSU_24840
Molecular weight
73.03 kDa
pI
4.82
function
biosynthesis of lipoteichoic acid
product
minor lipoteichoic acid synthase
essential
no
synonyms
yqgS
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1368 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,568,573 2,570,489
The protein
Protein family
[wiki|LTA synthase family] (according to UniProt)
Structure
[PDB|2W5Q] ([protein|418900B6DBDF3EF300C930B0C75E31B939F3CE00|ltaS] from S. aureus, corresponds to aa 218 ... 617 of [protein|2B33F2F9C2FB0767B72A29D060037393C88ACEE5|yqgS]) [pubmed|19168632]
[AF|P54496]
Modification
can be phosphorylated by [protein|23FF4A00C36EC1B7297F51A9EF3579B41F0B7EBA|prkC] in vitro [pubmed|30478337]
Paralogous protein(s)
[protein|418900B6DBDF3EF300C930B0C75E31B939F3CE00|ltaS], [protein|880C655DC7149F6EDC21BD2CF8F9F2C9FBEB2CDB|yvgJ], [protein|CCD06F344E3C87E77C3D13883CE2B927F372A84E|yfnI]
[wiki|Localization]
localizes to the division septum [Pubmed|19229300]
Expression and Regulation
Operons
genes
[gene|89C51789FBB2EE86771ABD8629FD99748ED5D4EF|yqgP]-[gene|C44F6723A2F1A627A0B9042871A07F5365D6121A|yqgO]-[gene|8E10A8B566BC25CBDDEF1503656A4234FD29ACB8|glcK]-[gene|2B33F2F9C2FB0767B72A29D060037393C88ACEE5|yqgS]
description
[pubmed|22383849]
additional information
[protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP]∼P binds to the promoter region, but regulation has not been explored [pubmed|25666134]
Biological materials
Mutant
MGNA-C419 (yqgS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2417 NBRP B. subtilis, Japan]
BKE24840 ([gene|2B33F2F9C2FB0767B72A29D060037393C88ACEE5|yqgS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACCTCCTATGCAG, downstream forward: _UP4_TAATCACAATGTCTCCCGCA
BKK24840 ([gene|2B33F2F9C2FB0767B72A29D060037393C88ACEE5|yqgS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACCTCCTATGCAG, downstream forward: _UP4_TAATCACAATGTCTCCCGCA
References
Reviews
Original Publications
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Time of last update: 2024-12-20 07:49:09
Author of last update: TPed