nadF

nadF
168

NAD kinase

Locus
BSU_11610
Molecular weight
29.86 kDa
Isoelectric point
5.99
Protein length
Gene length
Function
generation of NADP from NAD
Product
inorganic polyphosphate/ATP-NAD kinase
Essential
yes
E.C.
2.7.1.23
Synonyms
nadF, yjbN, ppnK, ppnKA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0061 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,237,660  1,238,460
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
ATP + NAD+ --> ADP + H+ + NADP+ (according to UniProt)
Protein family
NAD kinase family (with YtdI, according to UniProt)
Structure
2I1W (PDB) (from Listeria monocytogenes, 60% identity) PubMed
Effectors of protein activity
allosterically activated by quinolinic acid
Paralogous protein(s)
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Description
Regulation
expressed during exponential growth
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2024-12-26 12:34:19

Jstuelk

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Biological materials
Mutant
MGNA-B160 (yjbN::erm), available at the NBRP B. subtilis, Japan
1A825 ( nadF::erm), PubMed, available at BGSC
References
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2A2640A0501ECEA44A3C0C4842FAC053FB422A1F

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Time of last update: 2025-01-08 18:52:45

Author of last update: Melvin.boenninger