yhaR
168
similar to enoyl CoA hydratase
locus
BSU_09880
Molecular weight
27.47 kDa
pI
6.36
function
unknown
product
unknown
essential
no
synonyms
yhaR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1024 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,061,491 1,062,258
The protein
Protein family
[wiki|enoyl-CoA hydratase/isomerase family] (according to UniProt)
Structure
[PDB|3P5M] (from ''Mycobacterium avium'', 33% identity) [pubmed|25613812]
[AF|O07533]
Paralogous protein(s)
[protein|3111ECB66CD3CFF0494AA3DF4D646102CF3B0FA8|fadB], (34%)
[protein|D5CCFDE9312909B7E5B98876794569357791C76B|yngF], (34%)
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|25B45D6A90AD5152FDA71718B14767EA86ECA15B|yhaR]
description
[Pubmed|22383849]
regulation
expression during spore [wiki|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
Biological materials
Mutant
MGNA-B498 (yhaR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1497 NBRP B. subtilis, Japan]
BKE09880 ([gene|25B45D6A90AD5152FDA71718B14767EA86ECA15B|yhaR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAAAGCACCTCCATGT, downstream forward: _UP4_TAACAGATCAGCCGGAAAGC
BKK09880 ([gene|25B45D6A90AD5152FDA71718B14767EA86ECA15B|yhaR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAAAGCACCTCCATGT, downstream forward: _UP4_TAACAGATCAGCCGGAAAGC
References
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Time of last update: 2024-10-04 18:01:14
Author of last update: Melvin.boenninger