tpx

tpx
168

probable thiol peroxidase

locus
BSU_29490
Molecular weight
18.07 kDa
pI
4.7
Protein length
167 aaSequenceBlast
Gene length
504 bpSequenceBlast
function
unknown
product
unknown
essential
no
synonyms
tpx, ytgI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2077 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,017,696  3,018,199
The protein
Catalyzed reaction/ biological activity
[protein]-dithiol + hydroperoxide --> [protein]-disulfide + alcohol + H2O (according to UniProt)
Protein family
[wiki|peroxiredoxin family] (according to UniProt)
[wiki|Domains]
[wiki|Thioredoxin domain] (aa 18-167) (according to UniProt)
Structure
[PDB|2JSZ]
[AF|P80864]
Expression and Regulation
Operons
genes
[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]-[gene|2C83EECFA809F34ADCA6445CF2E6BAC730D523DB|ytxK]
description
[Pubmed|22383849]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [pubmed|12642660,19575568], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
Open in new tab

[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]→[gene|2C83EECFA809F34ADCA6445CF2E6BAC730D523DB|ytxK]

2024-12-21 16:54:55

Jstuelk

62

7fbd71a0dc51c44d0a5d6b85287eec2fe6db2d79

3F40B3FAFCCEFCAA3D5CE8250AA4915227F18104

genes
[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]
description
[Pubmed|9387221]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|12642660,19575568], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
Open in new tab

[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]

2024-12-17 04:33:46

ghost

66

39f441127623522a55edc7bb4ffe19aba6c89195

9C0F3827A1A8F8A92E28E2B9DF298EACAAD6F1E4

Biological materials
Mutant
MGNA-A113 (ytgI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/113 NBRP B. subtilis, Japan]
BKE29490 ([gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATAATTCCTCCCTTTT,  downstream forward: _UP4_TAAGCAGGGAAAAAAGCTCC
BKK29490 ([gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATAATTCCTCCCTTTT,  downstream forward: _UP4_TAAGCAGGGAAAAAAGCTCC
References
36815589,19636900,9387221,12642660

2501228D435B151F151A3C0EF10DE99A8395977F

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Time of last update: 2024-12-20 11:10:52

Author of last update: Jstuelk