cydD

cydD
168

ABC transporter required for expression of cytochrome bd ([metabolite|ATP]-binding protein)

locus
BSU_38730
Molecular weight
64.34 kDa
pI
6.22
Protein length
Gene length
function
required for expression of cytochrome bd
product
ABC transporter  ([metabolite|ATP]-binding protein)
essential
no
synonyms
cydD, yxkN

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4987 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,973,364  3,975,091
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
[wiki|ABC transmembrane type-1 domain] (aa 18-303) (according to UniProt)
[wiki|ABC transporter domain] (aa 337-570) (according to UniProt)
Structure
[PDB|2HYD] (from Staphylococcus aureus, 28% identity) [pubmed|16943773]
[AF|P94367]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|C0459C0D45E31561D281E016D86CD80DCAF13357|cydA]-[gene|E66EAB3C172ED8D1D26C675A7338B8153FB66987|cydB]-[gene|A65576E0261F1950A0DAD72B2432D97AB3EB2AA5|cydC]-[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]
description
[Pubmed|16207915]
regulation
expressed under anaerobic conditions ([protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]) [Pubmed|17322317]
expression
expression is heterogeneous [pubmed|35171018]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|B5EF521437323EF43F08E5EFDB5C798616CA499A|rex]: repression, [Pubmed|15231791], in [regulon|protein:B5EF521437323EF43F08E5EFDB5C798616CA499A|rex regulon]
[protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]: activation, [Pubmed|17322317], in [regulon|protein:1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD regulon]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [PubMed|16497325], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
Open in new tab

[gene|C0459C0D45E31561D281E016D86CD80DCAF13357|cydA]→[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]

2024-12-17 06:21:32

Jstuelk

111

B656DC522BB35F8FB6BB0C0BBC86CB05C20AB7C7

80895031322ED50D8EABA337924455145A6261DF

genes
[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]
description
[pubmed|16497325]
regulation
expressed under anaerobic conditions ([protein|search|ResD]) [Pubmed|17322317]
Open in new tab

[gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]

2024-12-22 06:15:08

ghost

58

765c002b93e0cb4b0e196e784f2352980c30c835

B02585BCF79AF3CD8A24E795FAC3C0504C9E4D44

Biological materials
Mutant
MGNA-B748 (cydD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1747 NBRP B. subtilis, Japan]
BKE38730 ([gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGGCAAAATCCATTCTTCTT,  downstream forward: _UP4_TAAAAGACAGCCCTAAAAGG
BKK38730 ([gene|244BF9E397FDB0691FFAA8C9D419B0AE417CACE1|cydD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGGCAAAATCCATTCTTCTT,  downstream forward: _UP4_TAAAAGACAGCCCTAAAAGG
References
15231791,16207915,17322317,10092453,16497325,9852001,15231791,17322317,24958725,16943773,39397791

244BF9E397FDB0691FFAA8C9D419B0AE417CACE1

Page visits: 4184

Time of last update: 2024-12-21 02:18:04

Author of last update: Jstuelk