jag
168
[protein|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-associated protein, similar to cell elongation regulator, similar to RNA-binding protein KhpB (from Streptococcus pneumoniae and Clostridium difficile)
locus
BSU_41030
Molecular weight
23.02 kDa
pI
10.04
function
unknown
product
[protein|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-associated protein
essential
no
synonyms
jag, khpB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1847 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,213,200 4,213,826
The protein
[wiki|Domains]
[wiki|KH domain] (aa 91-140) (according to UniProt)
R3H domain (aa 140-208) (according to UniProt)
Structure
[PDB|3GKU] (from Clostridium symbiosum, 40% identity)
[AF|Q01620]
Expression and Regulation
Operons
genes
[gene|EB07AECD3849CC0B65126DE27E71B28B3AD106B0|rpmH]-[gene|594F2D36BE71A45303A33AA2A2931F56F0A969ED|rnpA]-[gene|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-[gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]
description
[Pubmed|22383849]
regulation
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
genes
[gene|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-[gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]
description
[Pubmed|1487728]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|1487728], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
An antisense RNA is predicted for '[protein|search|jag]' [PubMed|20525796]
additional information
the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]
Biological materials
Mutant
MGNA-B878 (jag::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1877 NBRP B. subtilis, Japan]
BKE41030 ([gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE41030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCTCACTTTTTCTTTCCTCC, downstream forward: _UP4_TAGCATAAAACCGAAGTCCG
BKK41030 ([gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK41030 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCTCACTTTTTCTTTCCTCC, downstream forward: _UP4_TAGCATAAAACCGAAGTCCG
Reviews
References
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Time of last update: 2024-12-21 13:20:34
Author of last update: Jstuelk