yvaE
168
similar to multidrug-efflux transporter
locus
BSU_33570
Molecular weight
12.82 kDa
pI
8.13
function
unknown
product
subunit of unidentified multidrug transporter
essential
no
synonyms
yvaE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2076 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,448,693 3,449,052
The protein
Protein family
paired small multidrug resistance protein family ([wiki|PSMR family]) [Pubmed|17942072]
[wiki|drug/metabolite transporter (DMT) superfamily] (according to UniProt)
[wiki|Small multidrug resistance (SMR) (TC 2.A.7.1) family] (according to UniProt)
Structure
[PDB|3B5D] (from E. coli, 44% identity) [pubmed|18024586]
[AF|O32227]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|97CE9735931D02E6E780C955C9BE3A67E5C4C59A|yvaF]-[gene|230D790937DAFB82A04B8597699115E1C1EAE98E|yvaE]-[gene|B7FBC30B744D8B1F26AFC5DCB297FAFAB5C60FB7|yvaD]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-A502 (yvaE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/502 NBRP B. subtilis, Japan]
BKE33570 ([gene|230D790937DAFB82A04B8597699115E1C1EAE98E|yvaE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGCCAAGCATAGAAACACCC, downstream forward: _UP4_GTACATAAAAGCGGGCAGTA
BKK33570 ([gene|230D790937DAFB82A04B8597699115E1C1EAE98E|yvaE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGCCAAGCATAGAAACACCC, downstream forward: _UP4_GTACATAAAAGCGGGCAGTA
References
Reviews
Original Publications
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Time of last update: 2024-10-04 08:10:49
Author of last update: Melvin.boenninger