yebC2
168
resolves ribosome stalling at polyprolines
locus
BSU_06840
Molecular weight
26.23 kDa
pI
4.28
function
resolves ribosome stalling at polyprolines
product
translation factor
essential
no
synonyms
yeeI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0217 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
752,412 753,131
The protein
Catalyzed reaction/ biological activity
interacts with the 70S ribosome and prevents stalling at polypro line tracts [pubmed|39463947]
may be an RNA-binding protein [https://www.biorxiv.org/content/10.1101/2024.08.26.607280v1.full.pdf biorxiv]
Protein family
TACO1 family (with [protein|7F690393007F0BE9BC375256ECC59228AE5174B5|yrbC], according to UniProt)
Structure
[PDB|4F3Q] (YebC from Coxiella burnettii, 44% identity) [pubmed|26033498]
[AF|O31509]
Paralogous protein(s)
[protein|7F690393007F0BE9BC375256ECC59228AE5174B5|yrbC]
Expression and Regulation
Operons
genes
[gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A952 (yeeI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/952 NBRP B. subtilis, Japan]
BKE06840 ([gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGTTCCACTCTCTTT, downstream forward: _UP4_TAAGGAGTGAGCAGGCTGTT
BKK06840 ([gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGTTCCACTCTCTTT, downstream forward: _UP4_TAAGGAGTGAGCAGGCTGTT
References
Reviews
Original Publications
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Time of last update: 2024-12-20 10:12:29
Author of last update: Jstuelk