yebC2

yebC2
168

resolves ribosome stalling at polyprolines

locus
BSU_06840
Molecular weight
26.23 kDa
pI
4.28
Protein length
Gene length
function
resolves ribosome stalling at polyprolines
product
translation factor
essential
no
synonyms
yeeI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0217 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
752,412  753,131
The protein
Catalyzed reaction/ biological activity
interacts with the 70S ribosome and prevents stalling at polypro line tracts [pubmed|39463947]
may be an RNA-binding protein [https://www.biorxiv.org/content/10.1101/2024.08.26.607280v1.full.pdf biorxiv]
Protein family
TACO1 family (with [protein|7F690393007F0BE9BC375256ECC59228AE5174B5|yrbC], according to UniProt)
Structure
[PDB|4F3Q] (YebC from Coxiella burnettii, 44% identity) [pubmed|26033498]
[AF|O31509]
Paralogous protein(s)
[protein|7F690393007F0BE9BC375256ECC59228AE5174B5|yrbC]
Expression and Regulation
Operons
genes
[gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]
description
[Pubmed|22383849]
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[gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]

2024-12-21 16:37:42

Jstuelk

53

eed0e2cc714b3de71bfd8d95e528189b2768f53a

A24E61712B0A51F41B18096D0BDF51AD1425D393

Biological materials
Mutant
MGNA-A952 (yeeI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/952 NBRP B. subtilis, Japan]
BKE06840 ([gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06840 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGATGTTCCACTCTCTTT,  downstream forward: _UP4_TAAGGAGTGAGCAGGCTGTT
BKK06840 ([gene|227EC2A232A989ACE986726BD76CF5648C4CFA19|yebC2]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06840 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGATGTTCCACTCTCTTT,  downstream forward: _UP4_TAAGGAGTGAGCAGGCTGTT
References
Reviews
36882621
Original Publications
26033498,39463947

227EC2A232A989ACE986726BD76CF5648C4CFA19

Page visits: 1870

Time of last update: 2024-12-20 10:12:29

Author of last update: Jstuelk