sdpA
168
required for [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC] toxin maturation
locus
BSU_33750
Molecular weight
18.51 kDa
pI
9.77
function
maturation of the [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC] toxin
product
unknown
essential
no
synonyms
sdpA, yvaW
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
3,464,289 3,464,765
The protein
Structure
[AF|O34889]
Paralogous protein(s)
[protein|FBA412B070CE4FFE554F2657E0F745EF5C853B8A|yitP]
[wiki|Localization]
cytoplasm [Pubmed|23687264]
Expression and Regulation
Operons
genes
[gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]-[gene|073D63E17C8248BE39F331FDE9902E21A34056D5|sdpB]-[gene|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC]
description
[Pubmed|12817086]
regulation
expressed under conditions that trigger sporulation ([wiki|Spo0A]) [pubmed|14651647,15687200]
expression
expression is heterogeneous [pubmed|35171018]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: activation, [PubMed|14651647,15687200], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]
[protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|rok]: repression, [Pubmed|15743949], in [regulon|protein:1508770D5BCA5739D13E3ABD11CC5C103C07FF25|rok regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [PubMed|15687200,17720793], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
additional information
the amount of the mRNA is substantially decreased upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
Biological materials
Mutant
MGNA-A453 (yvaW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/453 NBRP B. subtilis, Japan]
BKE33750 ([gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACAGTAATAATTCCCT, downstream forward: _UP4_GTATGAAGATATTAAATAGT
BKK33750 ([gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33750 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTACAGTAATAATTCCCT, downstream forward: _UP4_GTATGAAGATATTAAATAGT
References
Reviews
Original Publications
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Time of last update: 2024-12-21 16:25:10
Author of last update: Jstuelk