abf2
168
alpha-L-arabinofuranosidase
locus
BSU_28510
Molecular weight
56.34 kDa
pI
5.33
function
arabinan degradation
product
alpha-L-arabinofuranosidase
essential
no
ec
3.2.1.55
synonyms
abf2, xsa
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3534 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,913,661 2,915,148
The protein
Catalyzed reaction/ biological activity
Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides (according to UniProt)
Protein family
glycosyl hydrolase 51 family (with [protein|2B2629D275491A9F7031D5A99BAA001B011A765B|abfA], according to UniProt)
Structure
[PDB|2VRQ] (from Thermobacillus xylanilyticus, 66% identity) [pubmed|18563919]
[AF|P94552]
Expression and Regulation
Operons
genes
[gene|1DF08A474E95909EAF68CF26D97DD49350ABEA89|abf2]
description
[Pubmed|14973026]
regulation
induced by arabinose ([protein|search|AraR]) [Pubmed|14973026]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|22900538], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|A567466894AE9DE7CDE7816615433A37532297B5|araR]: repression, [Pubmed|14973026], in [regulon|protein:A567466894AE9DE7CDE7816615433A37532297B5|araR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|14973026], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
A [protein|search|ncRNA] is predicted between '[protein|search|trxA]' and '[protein|search|abf2]' [PubMed|20525796]
Biological materials
Mutant
BKE28510 ([gene|1DF08A474E95909EAF68CF26D97DD49350ABEA89|abf2]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCTCTGATCATTCCTT, downstream forward: _UP4_TAATCGCGCAAGAGCGCCGG
BKK28510 ([gene|1DF08A474E95909EAF68CF26D97DD49350ABEA89|abf2]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCTCTGATCATTCCTT, downstream forward: _UP4_TAATCGCGCAAGAGCGCCGG
References
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Time of last update: 2024-12-21 19:45:01
Author of last update: Melvin.boenninger