qcrB
168
menaquinol:cytochrome c oxidoreductase (cytochrome b subunit), component of the cytochrome bc complex
locus
BSU_22550
Molecular weight
25.34 kDa
pI
7.44
function
respiration
product
menaquinol:cytochrome c oxidoreductase (cytochrome b subunit)
essential
no
synonyms
qcrB, bfcB, petB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1290 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,363,913 2,364,587
The protein
Protein family
cytochrome b family (with [protein|F2973C512AFB4B9F8FE0CCAF09646E60F886C013|qcrC], according to UniProt)
[wiki|Cofactors]
heme, covalently bound to Cys-43 [pubmed|9535866]
Structure
[PDB|1VF5] (from Mastigocladus laminosus, 43% identity) [pubmed|14526088]
[AF|P46912]
[wiki|Localization]
cell membrane [Pubmed|23880299]
Expression and Regulation
Operons
genes
[gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]-[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]-[gene|F2973C512AFB4B9F8FE0CCAF09646E60F886C013|qcrC]
description
[Pubmed|7592464]
regulation
induced by oxygen limitation ([protein|search|ResD]) [Pubmed|8631715]
regulatory mechanism
[protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]: activation, [Pubmed|8631715], in [regulon|protein:1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|12850135], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|7592464], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE22550 ([gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCAGTCATAAATTTTGTTCA, downstream forward: _UP4_TAAACTCTTGATCTGCGAAT
BKK22550 ([gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCAGTCATAAATTTTGTTCA, downstream forward: _UP4_TAAACTCTTGATCTGCGAAT
References
Reviews
Original Publications
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Time of last update: 2024-10-06 17:01:06
Author of last update: Jstuelk