levR
168
transcriptional activator of the [gene|75C568C8F6912AC064B8B435975D52510D25466A|levD]-[gene|CAE38D8F25A5EC6AC8045E40072E6FEC632045FA|levE]-[gene|8ABA3735067C7AA433E09F219EE7239196377A95|levF]-[gene|F23B951F60A6A669D5BD86836906E0F4AD7A0C1B|levG]-[gene|search|sacC ]operon
locus
BSU_27080
Molecular weight
105.99 kDa
pI
5.94
function
regulation of levan and fructose utilization
product
transcriptional activator, PRD-type (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|sigL]-dependent promoter)
essential
no
synonyms
levR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG3933 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,763,025 2,765,832
The protein
Catalyzed reaction/ biological activity
binding to the upstream activating sequence in front of the [gene|75C568C8F6912AC064B8B435975D52510D25466A|levD] gene results in activation of transcription of the [gene|75C568C8F6912AC064B8B435975D52510D25466A|levD]-[gene|CAE38D8F25A5EC6AC8045E40072E6FEC632045FA|levE]-[gene|8ABA3735067C7AA433E09F219EE7239196377A95|levF]-[gene|F23B951F60A6A669D5BD86836906E0F4AD7A0C1B|levG]-[gene|61D5B957E018D019AE0CE1D5F6C6A33EF982ED49|sacC] operon, bining occurs in the presence of fructose
Protein family
[wiki|Transcription factors activating transcription at SigL-dependent promoters]
[wiki|PRD-containing transcription factors] (according to UniProt)
[wiki|Domains]
[wiki|Sigma-54 factor interaction domain] (aa 117-348) (according to UniProt)
2 [wiki|PRD domain]s (aa 468-573, aa 831-935) (according to UniProt)
[wiki|PTS EIIA domain] type-4 (aa 574-711) (according to UniProt)
Structure
[AF|P23914]
Modification
phosphorylation (His503, His582, His866) (according to Swiss-Prot)
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|1D2043CC0D8CF64142F0A5993A936C5A196726D4|levR]
description
[pubmed|22383849]
Biological materials
Mutant
BKE27080 ([gene|1D2043CC0D8CF64142F0A5993A936C5A196726D4|levR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27080 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTCTATCATCCTTTGTC, downstream forward: _UP4_TAAAAACAGTTTTTTCATAT
BKK27080 ([gene|1D2043CC0D8CF64142F0A5993A936C5A196726D4|levR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27080 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTCTATCATCCTTTGTC, downstream forward: _UP4_TAAAAACAGTTTTTTCATAT
References
Page visits: 4751
Time of last update: 2024-10-07 14:37:13
Author of last update: Melvin.boenninger