cmk
168
cytidylate kinase (CMP, dCMP)
locus
BSU_22890
Molecular weight
24.95 kDa
pI
5
function
synthesis of CTP and dCTP
product
cytidylate kinase (CMP, dCMP)
essential
yes
ec
2.7.4.14
synonyms
cmk, jofC, ypfC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0283 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,396,045 2,396,719
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
ATP + CMP --> ADP + CDP (according to UniProt)
ATP + dCMP --> ADP + dCDP (according to UniProt)
Protein family
cytidylate kinase family (single member, according to UniProt)
Structure
[PDB|1CKE] (from ''Escherichia coli'', 38% identity, 54% similarity) [Pubmed|9862805]
[AF|P38493]
Expression and Regulation
Operons
genes
[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|rpsA]
description
[pubmed|22383849]
genes
[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|rpsA]-[gene|E91624382EC3DAABFB3123CDA818B4BEF745ACE6|fni]
description
[pubmed|22383849]
genes
[gene|C194336ED96FA844FFE9FB43BE59ADC5D6DDB3BE|motI]-[gene|3459BA0CDAABC288ADF97B111F78C7EAC184840D|ypfB]-[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|rpsA]-[gene|E91624382EC3DAABFB3123CDA818B4BEF745ACE6|fni]
description
[pubmed|22383849]
genes
[gene|C194336ED96FA844FFE9FB43BE59ADC5D6DDB3BE|motI]-[gene|3459BA0CDAABC288ADF97B111F78C7EAC184840D|ypfB]-[gene|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60|cmk]-[gene|7C36409F155E4C91CEE902FE6937571BD0C50128|rpsA]
description
[pubmed|22383849]
References
Page visits: 3327
Time of last update: 2024-10-04 23:11:10
Author of last update: Melvin.boenninger