ycnB
168
c-di-AMP exporter
locus
BSU_03840
Molecular weight
50.63 kDa
pI
10.83
function
secretion of cyclic di-AMP
product
c-di-AMP exporter
essential
no
synonyms
ycnB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
436,036 437,454
The protein
Catalyzed reaction/ biological activity
secretion of cyclic di-AMP [pubmed|29588402]
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
[wiki|EmrB family] (according to UniProt)
Structure
[AF|P94422]
Paralogous protein(s)
[protein|23483430AE0381406EF2349A18CFAE1F14F9B180|lmrB], [protein|93159DC7D5C42CFA54F66F232D73F38957243AB7|yhcA]
[wiki|Localization]
cell membrane (according to UniProt), membrane associated [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|C993D176CE1B93A74D34B45DFFE30295245E2BD2|ycnC]-[gene|188742B9A0C95344D32A4C23B9C971660572CF7D|ycnB]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-C012 (ycnB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2010 NBRP B. subtilis, Japan]
GP1702 (''[gene|188742B9A0C95344D32A4C23B9C971660572CF7D|ycnB]''::''spc''), available in [wiki|Jörg Stülke]'s lab
GP1703 (''[gene|23483430AE0381406EF2349A18CFAE1F14F9B180|lmrB]''::''aphA3'' ''[gene|188742B9A0C95344D32A4C23B9C971660572CF7D|ycnB]''::''spc''), available in [wiki|Jörg Stülke]'s lab
BKE03840 ([gene|188742B9A0C95344D32A4C23B9C971660572CF7D|ycnB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCAATACATATCCCTTCT, downstream forward: _UP4_TGATTAACAAAAAAAGAGCC
BKK03840 ([gene|188742B9A0C95344D32A4C23B9C971660572CF7D|ycnB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCAATACATATCCCTTCT, downstream forward: _UP4_TGATTAACAAAAAAAGAGCC
References
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Time of last update: 2024-12-30 15:43:16
Author of last update: Melvin.boenninger