kapB
168
activator of [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB], control of the [wiki|phosphorelay]
locus
BSU_31460
Molecular weight
14.53 kDa
pI
6.82
function
control of [wiki|sporulation] initiation
product
activator of [protein|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB] in the initiation of [wiki|sporulation]
essential
no
synonyms
kapB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
3,231,399 3,231,785
The protein
Structure
[PDB|1Y71] (from B. cereus, 61% identity)
[AF|Q08429]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|2111AC1AE49D1006E10DC127BF5B7A0327DE94A7|kinB]-[gene|18867F99B039D20DBCF004BC72E35CF0AE8FE467|kapB]
description
[Pubmed|8497199]
regulation
induced upon addition of decoyinine (positive [wiki|stringent response]) [Pubmed|23378509]
regulatory mechanism
[protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY]: repression, [Pubmed|12618455], in [regulon|protein:90ACE0DECA58D3C1A55E135120F7A0C1C920571C|codY regulon]
stringent response: positive regulation, [Pubmed|23378509], in [regulon|other_regulator:stringent response|stringent response]
[protein|5A6FBAE6553343092862CB79E150F934978C32A9|sinR]: repression, [pubmed|29321771], in [regulon|protein:5A6FBAE6553343092862CB79E150F934978C32A9|sinR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8497199], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE31460 ([gene|18867F99B039D20DBCF004BC72E35CF0AE8FE467|kapB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCATCACCTCGCAT, downstream forward: _UP4_TAACCCAGTCTGACAAAAGA
BKK31460 ([gene|18867F99B039D20DBCF004BC72E35CF0AE8FE467|kapB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCATCACCTCGCAT, downstream forward: _UP4_TAACCCAGTCTGACAAAAGA
References
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Time of last update: 2024-12-21 08:00:17
Author of last update: Jstuelk