yxnA
168
general stress protein, similar to ketoacyl reductase, survival of ethanol stress
locus
BSU_40000
Molecular weight
39.20 kDa
pI
9.31
function
survival of ethanol stress
product
unknown
essential
no
synonyms
yxnA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0300 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,108,058 4,109,128
The protein
Protein family
[wiki|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)
Structure
[PDB|4NBU] ([protein|439B468A13137000FB42E9389391CB4986FFED84|fabG] from Bacillus sp., corresponds to aa 26 ... 255 of YxnA, 32% identity) [pubmed|24212572]
[AF|O32291]
Paralogous protein(s)
[protein|0927C7D45721F47F5ED2646CAAC324A308FD7724|yqjQ], (32,1%)
Expression and Regulation
Operons
genes
[gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]
description
[Pubmed|10746760]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
Biological materials
Mutant
MGNA-B762 (yxnA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1761 NBRP B. subtilis, Japan]
BKE40000 ([gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAGAGATCCCTCCTAG, downstream forward: _UP4_TAATCTCTGACCATAAGAAA
BKK40000 ([gene|18698DA427051097DEEE63F45F3429B8617B1F48|yxnA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAGAGATCCCTCCTAG, downstream forward: _UP4_TAATCTCTGACCATAAGAAA
References
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Time of last update: 2024-12-21 02:23:16
Author of last update: Jstuelk