dapF
168
diaminopimelate epimerase
locus
BSU_32170
Molecular weight
30.72 kDa
pI
4.51
function
biosynthesis of lysine and peptidoglycan
product
diaminopimelate epimerase
essential
yes
ec
5.1.1.7
synonyms
dapF, yutL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0253 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,306,040 3,306,894
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
LL-2,6-diaminoheptanedioate --> meso-2,6-diaminopimelate (according to UniProt)
Protein family
diaminopimelate epimerase family (single member, according to UniProt)
Structure
[PDB|2OTN] (from ''Bacillus anthracis str. ames'', 62% identity, 75% similarity)
[AF|O32114]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|185B6596F0468B76BCA85E8753063FAE83445E18|dapF]-[gene|94A3B5EF4ADCFA57A204B584B6D305A62E3E15AE|sufA]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B574 (yutL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1573 NBRP B. subtilis, Japan]
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Time of last update: 2024-10-13 14:51:51
Author of last update: Melvin.boenninger