iolQ
168
transcriptional repressor of [gene|AA7DCEFB17FD6F9C4F65235E9A247A6EC2242B06|iolX] expression, transcriptional activator involved in the degradation of glutamine phosphoribosylpyrophosphate amidotransferase
locus
BSU_10840
Molecular weight
36.44 kDa
pI
5.78
function
control of scyllo-inositol utilization
product
transcription factor ([wiki|LacI family])
essential
no
synonyms
iolQ, degA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,163,148 1,164,161
The protein
Catalyzed reaction/ biological activity
binds to [gene|AA7DCEFB17FD6F9C4F65235E9A247A6EC2242B06|iolX] promoter region [pubmed|28693424]
[wiki|Domains]
[wiki|HTH lacI-type domain] (aa 1-57) (according to UniProt)
Structure
[PDB|2HSG] ([protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA], 35% identity) [pubmed|17500051]
[AF|P37947]
Expression and Regulation
Operons
genes
[gene|5B173B400D0B4C150E94A98D35E27B0B4358489B|yisR]-[gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]
description
[pubmed|22383849]
additional information
the mRNA is very stable (> 15 min) [pubmed|12884008]
Biological materials
Mutant
BKE10840 ([gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATGTTCATCCCTCGTC, downstream forward: _UP4_TGAGCCCGCTAATGAGCGGG
BKK10840 ([gene|17F5188958A415D8D09439E02E1D1E0661B5C760|iolQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTCATGTTCATCCCTCGTC, downstream forward: _UP4_TGAGCCCGCTAATGAGCGGG
References
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Time of last update: 2025-04-19 14:53:11
Author of last update: Jstuelk