yacL
168
general stress protein, survival of salt and ethanol stresses
locus
BSU_00890
Molecular weight
40.70 kDa
pI
4.97
function
survival of salt and ethanol stresses
product
unknown
essential
no
ec
null
synonyms
yacL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4956 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
108,674 109,774
The protein
Protein family
Ycf81 family (single member, according to UniProt)
[wiki|Domains]
PINc domain (aa 169-280) ( according to UniProt)
[wiki|TRAM domain] (aa 295-356) (according to UniProt)
Structure
[PDB|3IX7] (from Thermus thermophilus, corresponds to aa 168 ... 294, 45% identity)
[AF|Q06754]
Expression and Regulation
Operons
genes
[gene|179FDEA51A060DF32A3EA06A796793DE27B600FF|yacL]-[gene|CF9633F769263C6D16EE778F6BD2ECF1995F512A|ispD]-[gene|1A6793A3A5AC568C67873C8708E9F581F42AB9BA|ispF]
description
[Pubmed|10482513]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|17434969], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
Biological materials
Mutant
MGNA-B933 (yacL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1932 NBRP B. subtilis, Japan]
BKE00890 ([gene|179FDEA51A060DF32A3EA06A796793DE27B600FF|yacL]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACCCCCACCTCCTTTTT, downstream forward: _UP4_GCGCTGTAAAGGGAGAAGAA
BKK00890 ([gene|179FDEA51A060DF32A3EA06A796793DE27B600FF|yacL]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACCCCCACCTCCTTTTT, downstream forward: _UP4_GCGCTGTAAAGGGAGAAGAA
References
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Time of last update: 2024-10-11 23:05:06
Author of last update: Melvin.boenninger