ydgH
168
similar to drug exporter
locus
BSU_05650
Molecular weight
95.29 kDa
pI
5.14
function
unknown
product
unknown
essential
no
ec
null
synonyms
ydgH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2409 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
609,388 612,045
The protein
Protein family
resistance-nodulation-cell division (RND) (TC 2.A.6) family (with [protein|1B61298ECA583D2112AA56A88358E8A9A55D2C9D|ydfJ] and [protein|AAC32230E3E585932A876737131C3E2C15168B2A|swrC], according to UniProt)
Structure
[PDB|6AJF] (from Mycobacterium smegmatis, corresponds to aa 2 ... 370 and 686 ... 885, 24% identity) [pubmed|30682372]
[AF|P96706]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|833F4B9ECB609D5EBAD0CAA55E1F601A5C1C3787|ydgG]-[gene|1632474628BEA113F297897D152276A1AB73BAE8|ydgH]
description
[Pubmed|16267290]
regulation
induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [Pubmed|16267290], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
Biological materials
Mutant
MGNA-C161 (ydgH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2159 NBRP B. subtilis, Japan]
BKE05650 ([gene|1632474628BEA113F297897D152276A1AB73BAE8|ydgH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCACTTGAATTTGATGATTG, downstream forward: _UP4_TAATCGAGAGAAGAGTGATG
BKK05650 ([gene|1632474628BEA113F297897D152276A1AB73BAE8|ydgH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05650 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCACTTGAATTTGATGATTG, downstream forward: _UP4_TAATCGAGAGAAGAGTGATG
References
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Time of last update: 2024-10-12 09:26:39
Author of last update: Jstuelk