oxdD
168
oxalate decarboxylase, inner spore coat protein
locus
BSU_18670
Molecular weight
43.39 kDa
pI
5.36
function
protection of the spore
product
oxalate decarboxylase
essential
no
ec
4.1.1.2
synonyms
oxdD, yoaN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2140 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,037,601 2,038,779
The protein
Catalyzed reaction/ biological activity
H+ + oxalate --> CO2 + formate (according to UniProt)
Structure
[PDB|1L3J] ([protein|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC], 59% identity) [pubmed|14871895]
[AF|O34767]
Paralogous protein(s)
[protein|9793E952C985BA268AC28C907900A03F4E8A3253|oxdC]
[wiki|Localization]
inner spore coat, localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA] [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|1568DD457FDD482B3C14954A95F62BE338CBD15D|oxdD]
description
[Pubmed|14973022]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|14973022]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|14973022], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,14973022], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-A842 (yoaN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/842 NBRP B. subtilis, Japan]
BKE18670 ([gene|1568DD457FDD482B3C14954A95F62BE338CBD15D|oxdD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCACCTCGTTTTAGAAA, downstream forward: _UP4_TAAAGACGTAACAGATCACA
BKK18670 ([gene|1568DD457FDD482B3C14954A95F62BE338CBD15D|oxdD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCACCTCGTTTTAGAAA, downstream forward: _UP4_TAAAGACGTAACAGATCACA
References
Reviews
Original Publications
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Time of last update: 2024-12-19 16:05:38
Author of last update: Melvin.boenninger