opuBD

opuBD
168

choline and arsenocholine [wiki|ABC transporter] (membrane protein)

locus
BSU_33700
Molecular weight
23.78 kDa
pI
10.06
Protein length
Gene length
function
compatible solute transport
product
choline and arsenocholine [wiki|ABC transporter] (membrane protein)
essential
no
synonyms
opuBD, proZ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1174 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,459,806  3,460,486
The protein
Catalyzed reaction/ biological activity
uptake of choline and arsenocholine [pubmed|29159878]
Protein family
[wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
[wiki|CysTW subfamily] (according to UniProt)
[wiki|Domains]
[wiki|ABC transmembrane type-1 domain] (aa 22-202) (according to UniProt)
Structure
[AF|P39775]
Paralogous protein(s)
[protein|76C8D6BF2CA1FA5E7392C52FFD55FD01EF5AB9DC|opuCD]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|3F502A4DCB1DAD7C3F968465B13C35213240515B|opuBA]-[gene|70B45E7428DB1F6AEF7D2FE3062CC86BE96674FC|opuBB]-[gene|C48798FE13B1521236F5BC5786B9A02D7BC9A336|opuBC]-[gene|1532EC3D741C5AB3D0B642741218FAE00AD460FA|opuBD]
description
[Pubmed|10216873]
regulation
induced by choline ([protein|search|GbsR]) [Pubmed|22408163]
regulatory mechanism
[protein|5C398C1181CE25CAC079AFBA5871C0B72AE1AA96|gbsR]: repression, (transcriptional roadblock) [Pubmed|32849357,22408163], in [regulon|protein:5C398C1181CE25CAC079AFBA5871C0B72AE1AA96|gbsR regulon]
[protein|9F32E96AC9C32832C2F10FB125DDDC50EC9B546B|opcR]: repression, (sterical interference with RNA polymerase access) [Pubmed|32849357,23960087], in [regulon|protein:9F32E96AC9C32832C2F10FB125DDDC50EC9B546B|opcR regulon]
[protein|6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA]: activation, [Pubmed|23646920], in [regulon|protein:6AF1CB8998BE9C71DF4F1201A7F74FF7E75CB799|remA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10216873], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
An antisense RNA is predicted for'[protein|search|opuBD]' [PubMed|20525796]
Open in new tab

[gene|3F502A4DCB1DAD7C3F968465B13C35213240515B|opuBA]→[gene|1532EC3D741C5AB3D0B642741218FAE00AD460FA|opuBD]

2024-10-09 05:21:45

ghost

76

f5d474616565c5e32550f1c34aef09f972669a8e

1F7D81939583251B3B9B9F3D0D915C77CF89D428

Biological materials
Mutant
BKE33700 ([gene|1532EC3D741C5AB3D0B642741218FAE00AD460FA|opuBD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33700 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACGTTCATTGACCTCTTCC,  downstream forward: _UP4_TAGAATAGAAAAAGAGGCTG
BKK33700 ([gene|1532EC3D741C5AB3D0B642741218FAE00AD460FA|opuBD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33700 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACGTTCATTGACCTCTTCC,  downstream forward: _UP4_TAGAATAGAAAAAGAGGCTG
References
Reviews
27935846
Original Publications
10092453,9925583,10216873,21296969,20525796,22408163,23960087,23646920,29159878,32373088,36815589

1532EC3D741C5AB3D0B642741218FAE00AD460FA

Page visits: 2703

Time of last update: 2024-10-13 07:14:40

Author of last update: Jstuelk