yhfQ
168
iron/ citrate [wiki|ABC transporter] (solute-binding protein)
locus
BSU_10330
Molecular weight
38.39 kDa
pI
9.3
function
iron uptake
product
iron/ citrate [wiki|ABC transporter] (solute-binding protein)
essential
no
synonyms
yhfQ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4594 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,107,733 1,108,704
The protein
Protein family
[wiki|Bacterial solute-binding protein 8 family] (according to UniProt)
[wiki|Domains]
[wiki|Fe/B12 periplasmic-binding domain] (aa 51-322) (according to UniProt)
Structure
[PDB|3EIW] (from ''Staphylococcus aureus'', the [protein|569510093E5B69A0368205920A21A81CADF030E9|fecC]-[protein|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ] complex, 39% identity) [Pubmed|19400778]
[AF|C0SP94]
Paralogous protein(s)
[protein|569510093E5B69A0368205920A21A81CADF030E9|fecC]
[wiki|Localization]
associated to the membrane (via [protein|BDAA56484E05DA3C1CB0CA09873A365657999679|fecD]-[protein|800EAB1D8617589CCAC68FB874EFCDE4C77962E1|fecE]) [Pubmed|10092453,18763711]
Expression and Regulation
Operons
genes
[gene|DCA3A7605CA19FAF61BDB75421BD41F11CB638E5|yhfO]-[gene|FE034FDCEAD4F4E91FD0147E16685632069E3316|yhfP]-[gene|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ]
description
[Pubmed|22383849]
genes
[gene|FE034FDCEAD4F4E91FD0147E16685632069E3316|yhfP]-[gene|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ]
description
[Pubmed|22383849]
genes
[gene|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ]
description
[pubmed|22383849]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
Biological materials
Mutant
MGNA-B278 (yhfQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1277 NBRP B. subtilis, Japan]
BKE10330 ([gene|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTTCCAGTCTCTCCT, downstream forward: _UP4_TAAAAGAAAAGACAGGCAAA
BKK10330 ([gene|1469148C83B1704E721652203EA31F0E2C33FDC6|yhfQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTTCCAGTCTCTCCT, downstream forward: _UP4_TAAAAGAAAAGACAGGCAAA
References
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Time of last update: 2024-10-12 11:20:55
Author of last update: Melvin.boenninger