ywcE
168
holin, required for spore morphogenesis and germination
locus
BSU_38130
Molecular weight
9.82 kDa
pI
9.85
function
required for spore morphogenesis and germination
product
holin
essential
no
synonyms
ywcE, ipa-41r
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
3,914,009 3,914,272
Phenotypes of a mutant
forms spores with a reduced outer coat [pubmed|16159778]
The protein
Protein family
ywcE family (single member, according to UniProt)
Structure
[AF|P39603]
[wiki|Localization]
cell membrane [pubmed|16159778]
spore core membran [pubmed|16159778]
spore outer membran [pubmed|16159778]
Expression and Regulation
Operons
genes
[gene|1426D5E85EA17234A3E2C98018DA99437F8E712C|ywcE]
description
[Pubmed|9353933]
regulation
repressed during the log phase ([protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]), expressed only at the onset of stationary phase [Pubmed|16159778]
repressed under anaerobic conditions ([protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]) [pubmed|28439033]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|16159778], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
[protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD]: repression, [pubmed|28439033], in [regulon|protein:1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|resD regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16159778], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE38130 ([gene|1426D5E85EA17234A3E2C98018DA99437F8E712C|ywcE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACCCGTCTCCTTTCATT, downstream forward: _UP4_TGAAGACAGCAAAAAACCCT
BKK38130 ([gene|1426D5E85EA17234A3E2C98018DA99437F8E712C|ywcE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38130 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACCCGTCTCCTTTCATT, downstream forward: _UP4_TGAAGACAGCAAAAAACCCT
labs
[wiki|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
References
Page visits: 3298
Time of last update: 2024-10-14 10:34:15
Author of last update: Melvin.boenninger