amj

amj
168

lipid II flippase, alternative to [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]

locus
BSU_04230
Molecular weight
29.30 kDa
pI
10.6
Protein length
Gene length
function
export of lipid II
product
lipid II flippase
essential
no
synonyms
amj, ydaH

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
474,731  475,540
Phenotypes of a mutant
an ''[gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj] [gene|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]'' double mutant is not viable [Pubmed|25918422]
inactivation suppresses the essentiality of [gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl] [pubmed|39185233]
The protein
Protein family
Amj family (single member, according to UniProt)
Structure
[AF|P96581]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]
description
[Pubmed|17434969]
regulation
induced in the stationary phase due to the internal production of toxic peptides ([wiki|SdpC], [wiki|SkfA]) [Pubmed|26364265]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|17434969], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
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[gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]

2024-09-22 09:12:31

ghost

61

2fb98912c757655c091cccff910aa6f18d266ad9

DAC6DD2DC445A62F07AA552D0C13800A026DA3ED

Biological materials
Mutant
MGNA-C089 (ydaH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2087 NBRP B. subtilis, Japan]
BKE04230 ([gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT,  downstream forward: _UP4_TAATAAGAAAGGCTGGATCA
BKK04230 ([gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT,  downstream forward: _UP4_TAATAAGAAAGGCTGGATCA
References
Reviews
26679002,28975672,37238589
Original Publications
17434969,25918422,17434969,26364265,39185233

12DB5AF311932991B66716BBCD08DA2C45B43BB9

Page visits: 3878

Time of last update: 2024-10-08 04:20:59

Author of last update: Jstuelk