amj
168
lipid II flippase, alternative to [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]
locus
BSU_04230
Molecular weight
29.30 kDa
pI
10.6
function
export of lipid II
product
lipid II flippase
essential
no
synonyms
amj, ydaH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
474,731 475,540
Phenotypes of a mutant
an ''[gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj] [gene|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|murJ]'' double mutant is not viable [Pubmed|25918422]
inactivation suppresses the essentiality of [gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl] [pubmed|39185233]
The protein
Protein family
Amj family (single member, according to UniProt)
Structure
[AF|P96581]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]
description
[Pubmed|17434969]
regulation
induced in the stationary phase due to the internal production of toxic peptides ([wiki|SdpC], [wiki|SkfA]) [Pubmed|26364265]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|17434969], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
Biological materials
Mutant
MGNA-C089 (ydaH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2087 NBRP B. subtilis, Japan]
BKE04230 ([gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE04230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT, downstream forward: _UP4_TAATAAGAAAGGCTGGATCA
BKK04230 ([gene|12DB5AF311932991B66716BBCD08DA2C45B43BB9|amj]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK04230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTATTCTTCCTCCAAT, downstream forward: _UP4_TAATAAGAAAGGCTGGATCA
References
Reviews
Original Publications
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Time of last update: 2024-12-30 02:07:46
Author of last update: Jstuelk