murR
168
transcriptional repressor of genes required for the utilization of N-acetylmuramic acid
locus
BSU_01690
Molecular weight
30.56 kDa
pI
6.87
function
regulation of muramic acid utilization
product
transcriptional repressor
essential
no
synonyms
murR, ybbH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1737 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
191,183 192,034
The protein
[wiki|Domains]
HTH rpiR-type domain (aa 3-79) (according to UniProt)
[wiki|SIS domain] (aa 123-264) (according to UniProt)
Structure
[PDB|2O3F] (N-terminal domain)
[AF|Q45581]
Expression and Regulation
Operons
genes
[gene|0B1F43F43A4DC1574A153DBFBAA5D0A1855F9B61|murQ]-[gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]-[gene|178D5E2AA1225FE909E6F2B63B3595F5ABB8E7A2|murP]-[gene|DEACFD435DB01C4B3ADEF397BEE08E2E7C7FCC36|amiE]-[gene|A5D4BF262BD365DCEBA9358C8DB295E605DE4D84|nagZ]-[gene|005D37F34CA3D6891F7D8FF7A2AFA1CBCB556FFE|namZ]
description
[Pubmed|22383849]
regulation
expressed in late exponential and early stationary phase [Pubmed|20400549]
regulatory mechanism
[protein|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]: repression, [pubmed|30038046], in [regulon|protein:125872506C400CB6B3DAEA8B5130B064DFBA4494|murR regulon]
Biological materials
Mutant
MGNA-B951 (ybbH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1950 NBRP B. subtilis, Japan]
BKE01690 ([gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE01690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTGGCCATTCTAGTTCTCT, downstream forward: _UP4_TAAGGCATCTTGAAGGGGAG
BKK01690 ([gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK01690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TGTGGCCATTCTAGTTCTCT, downstream forward: _UP4_TAAGGCATCTTGAAGGGGAG
References
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Time of last update: 2024-12-19 15:05:25
Author of last update: Melvin.boenninger