cheR
168
MCPs methyltransferase
locus
BSU_22720
Molecular weight
29.80 kDa
pI
9.25
function
motility, chemotaxis
product
MCPs methyltransferase
essential
no
ec
2.1.1.80
synonyms
cheR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1352 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,380,347 2,381,117
The protein
Catalyzed reaction/ biological activity
methylation of specific glutamate residues in the cytoplasmic domain of methyl-accepting chemotactic protein receptors (MCPRs)
L-glutamyl-[protein] + S-adenosyl-L-methionine --> [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine (according to UniProt)
[wiki|Domains]
CheR-type methyltransferase domain (aa 1-256) (according to UniProt)
Structure
[PDB|5FTW] (complex with S-adenosyl-L-homocysteine)
[AF|P31105]
Expression and Regulation
Operons
genes
[gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]-[gene|9712D0E655289C97315314BDEE1A0DF2ED2ADCA2|aroF]-[gene|58B782C1F7931F8671161455E65E3D5C72B0BB9C|aroB]-[gene|5C2F7F9F5FCBFEDF77AC41725EFDA0FAF0FC3BC1|aroH]
description
[pubmed|22383849]
Biological materials
Mutant
1A830 ( ''cheR''::''cat''), [Pubmed|8244966], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A830&Search=1A830 BGSC]
BKE22720 ([gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTACTCTCCCAGTCT, downstream forward: _UP4_TAGACTGACTTTTTGCTGAA
BKK22720 ([gene|1217807AE3AE3A654BA0DD4AF5ADF1CEE62632B6|cheR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22720 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTACTCTCCCAGTCT, downstream forward: _UP4_TAGACTGACTTTTTGCTGAA
References
Reviews
Original Publications
Page visits: 1922
Time of last update: 2024-10-14 17:37:37
Author of last update: Melvin.boenninger