ygaK
168
uncharacterized FAD-linked oxidoreductase
locus
BSU_08800
Molecular weight
40.96 kDa
pI
7.12
function
unknown
product
unknown
essential
no
synonyms
ygaK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0277 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
957,705 959,060
The protein
Protein family
oxygen-dependent FAD-linked oxidoreductase family (with [protein|23F2385D14DDD5C400DC897E0F0FC814ACFC36B8|yitY] and [protein|C4CC3772CA9FC46D90D2F15AE261106A0BC4453C|cotQ], according to UniProt)
[wiki|Domains]
[wiki|FAD-binding PCMH-type domain] (aa 29-204) (according to UniProt)
[wiki|Cofactors]
FAD (according to UniProt)
Structure
[PDB|3W8W] (from ''Streptomyces maritimus'', 33%)
[AF|Q796Y5]
Paralogous protein(s)
[protein|C4CC3772CA9FC46D90D2F15AE261106A0BC4453C|cotQ], (40%)
Expression and Regulation
Operons
genes
[gene|11499CDC836A40E857B8F5AD746BA2C650DC916B|ygaK]
description
[Pubmed|22383849]
regulation
expression during spore [wiki|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
Biological materials
Mutant
MGNA-A246 (ygaK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/246 NBRP B. subtilis, Japan]
BKE08800 ([gene|11499CDC836A40E857B8F5AD746BA2C650DC916B|ygaK]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACACTCCCACATCTCTTTC, downstream forward: _UP4_TAAAAAAATGAAGATGGAGC
BKK08800 ([gene|11499CDC836A40E857B8F5AD746BA2C650DC916B|ygaK]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACACTCCCACATCTCTTTC, downstream forward: _UP4_TAAAAAAATGAAGATGGAGC
References
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Time of last update: 2024-10-03 16:48:33
Author of last update: Melvin.boenninger