ygaD
168
similar to [wiki|ABC transporter] (fused [metabolite|ATP]-binding and membrane protein)
locus
BSU_08690
Molecular weight
66.59 kDa
pI
7.03
function
unknown
product
[wiki|ABC transporter] (fused ATP-binding and membrane protein)
essential
no
synonyms
ygaD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1132 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
939,322 941,091
The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
[wiki|ABC transmembrane type-1 domain] (aa 19-307) (according to UniProt)
[wiki|ABC transporter domain] (aa 341-576) (according to UniProt)
Structure
[PDB|2HYD] (from Staphylococcus aureus, 61% identity) [pubmed|16943773]
[AF|P71082]
Paralogous protein(s)
[protein|288CA73D93B1E5106E1C6CE5E7E2E8BE2A6BD3F3|yfiB], [protein|67C0C9EA17EF953554D3D57CD0D285246F50C1AD|bmrC], [protein|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU], [protein|9B2766D2F8892AA17DB480216570C81C33355C3B|bmrD], [protein|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV], [protein|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA], [protein|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC], [protein|ED1F82463BAA28B67184BFAB5CB23CF26A62999D|bmrA]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|FFC7595CD0930089B768BB36816A3FE470501236|ygaC]-[gene|0EB4D3E1B9AF39ECCBD79EB559FAE5BB0EE4C156|ygaD]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A244 (ygaD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/244 NBRP B. subtilis, Japan]
BKE08690 ([gene|0EB4D3E1B9AF39ECCBD79EB559FAE5BB0EE4C156|ygaD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08690 BGSC] and in [wiki|Jörg Stülke]'s lab, [Pubmed|28189581], upstream reverse: _UP1_CACGGTTGATTCCCCCTCTC, downstream forward: _UP4_TAAAACATCAATCTTATATC
BKK08690 ([gene|0EB4D3E1B9AF39ECCBD79EB559FAE5BB0EE4C156|ygaD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGGTTGATTCCCCCTCTC, downstream forward: _UP4_TAAAACATCAATCTTATATC
two-hybrid system
B. pertussis adenylate cyclase-based bacterial two hybrid system ([wiki|BACTH]), available in [wiki|Jörg Stülke]'s lab
References
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Time of last update: 2024-12-21 04:37:25
Author of last update: Jstuelk