dgk
168
deoxyguanosine kinase
locus
BSU_00150
Molecular weight
24.00 kDa
pI
5.78
function
purine salvage and interconversion
product
deoxyguanosine kinase
essential
no
ec
2.7.1.113
synonyms
dgk, yaaG
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1428 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
23,146 23,769
The protein
Catalyzed reaction/ biological activity
ATP + deoxyguanosine = ADP + dGMP (according to UniProt)
Protein family
DCK/DGK family (together woth [protein|D749382783437F40AE1C66755F57D44E3FCA193F|dck]) (accoding to UniProt)
Structure
[PDB|8PUU] (from Giardia intestinalis , 33% identity)
[AF|P37530]
Paralogous protein(s)
[protein|D749382783437F40AE1C66755F57D44E3FCA193F|dck]
[wiki|Localization]
cytoplasm (accoding to UniProt)
Expression and Regulation
Operons
genes
[gene|0DA340B3D23B63C6BD284BF86409558A31B12B53|dgk]-[gene|D749382783437F40AE1C66755F57D44E3FCA193F|dck]
description
[pubmed|22383849]
Biological materials
Mutant
MGNA-B888 (yaaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1887 NBRP B. subtilis, Japan]
BKE00150 ([gene|0DA340B3D23B63C6BD284BF86409558A31B12B53|dgk]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGAATCCTCCTTATAT, downstream forward: _UP4_GCCCATGTAAAGGAGCTTAT
BKK00150 ([gene|0DA340B3D23B63C6BD284BF86409558A31B12B53|dgk]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGAATCCTCCTTATAT, downstream forward: _UP4_GCCCATGTAAAGGAGCTTAT
References
Page visits: 2019
Time of last update: 2024-12-26 06:58:56
Author of last update: Jstuelk