fruC
168
fructokinase
locus
BSU_06170
Molecular weight
34.10 kDa
pI
4.62
function
utilization of sucrose and glucitol
product
fructokinase
essential
no
synonyms
fruC, ydjE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0524 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
670,087 671,049
The protein
Catalyzed reaction/ biological activity
Fru Fru-6-P
Protein family
[wiki|carbohydrate kinase PfkB family] (according to UniProt)
Structure
[PDB|5EY7] (from Vibrio cholerae, 38% identity)
[AF|O34768]
Expression and Regulation
Operons
genes
[gene|2E9D10B0FA5685800007222A5AAD71E975675DB1|gutB]-[gene|B13F7C35FBD55C674E5B19836D32279E7C1A5520|gutP]-[gene|0C4F0C9EF18FB4E9BB5BC3F53F7DDF5F32B51FA5|fruC]
description
[Pubmed|22383849]
regulation
induced by glucitol ([protein|926BCA197F259558F72FDCC73998497B9B167D22|gutR]) [Pubmed|8195086]
regulatory mechanism
[protein|926BCA197F259558F72FDCC73998497B9B167D22|gutR]: activation, [Pubmed|8195086], in [regulon|protein:926BCA197F259558F72FDCC73998497B9B167D22|gutR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8195086], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|0C4F0C9EF18FB4E9BB5BC3F53F7DDF5F32B51FA5|fruC]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-C213 (ydjE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2211 NBRP B. subtilis, Japan]
BKE06170 ([gene|0C4F0C9EF18FB4E9BB5BC3F53F7DDF5F32B51FA5|fruC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCACACTCATTTA, downstream forward: _UP4_TAAATCATTGAAGATGTTTC
BKK06170 ([gene|0C4F0C9EF18FB4E9BB5BC3F53F7DDF5F32B51FA5|fruC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTATCACACTCATTTA, downstream forward: _UP4_TAAATCATTGAAGATGTTTC
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Time of last update: 2025-04-03 11:50:54
Author of last update: Jstuelk