glpX

glpX
168

class II fructose-1,6-bisphosphatase, gluconeogenesis

locus
BSU_37090
Molecular weight
33.80 kDa
pI
5.07
Protein length
Gene length
function
gluconeogenesis
product
class II fructose-1,6-bisphosphatase
essential
no
ec
3.1.3.11
synonyms
glpX, ywjI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1494 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,805,090  3,806,055
The protein
Catalyzed reaction/ biological activity
β-D-fructose 1,6-bisphosphate + H2O --> β-D-fructose 6-phosphate + phosphate (according to UniProt)
Protein family
FBPase class 2 family (single member, according to UniProt)
Structure
[PDB|3D1R]  (from ''E. coli'', 49% identity, 68% similarity)[Pubmed|19073594]
[AF|Q03224]
Kinetic information
K(M) for FBP: 20 M  [Pubmed|19270101]
Expression and Regulation
Operons
genes
[gene|523B01B5E7141C7DFC28CE67EB92580F49C20844|murAB]-[gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]
description
[Pubmed|19270101]
regulation
constitutive [Pubmed|19270101]
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[gene|523B01B5E7141C7DFC28CE67EB92580F49C20844|murAB]→[gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]

2024-10-02 12:13:24

ghost

95

68c6b98587a1a4adea7c4517bd8cc72d68d97720

960C582131BBFA4675CD61E432271CA919997E2D

Biological materials
Mutant
MGNA-B658 (ywjI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1657 NBRP B. subtilis, Japan]
BKE37090 ([gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37090 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACACGATCTCCTC,  downstream forward: _UP4_TAACAAACAGAAAAAGCGGG
BKK37090 ([gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37090 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACACGATCTCCTC,  downstream forward: _UP4_TAACAAACAGAAAAAGCGGG
References
19270101,19073594

0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD

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Time of last update: 2024-10-09 10:38:47

Author of last update: Melvin.boenninger