Explore the novel features of the upcoming release of in its beta version,
SubtiWiki v5! It features genomic conservation, interaction of proteins with metabolites, dedicated metabolite pages, and much more!
Check the pages for
MntR and
manganese!
yueB
168
membrane protein, part of the type VII protein secretion system [protein|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]-[protein|3FE4A91C7D0B43C8704391F2F9493852B3AED9B0|essB]-[protein|6007664F3D979B4D8D4662C7F6E5CF2F489268E3|yukB]-[protein|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]-[protein|DA52C4CD130F32734E01A52F2F395127D2260F61|yueC], receptor for phage SPPI
Molecular weight
119.77 kDa
function
export of [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]
product
part of the type VII protein secretion system, receptor for phage SPPI
Genomic Context
This gene is a member of the following
regulons
Gene
Coordinates
3,266,687 3,269,917
Phenotypes of a mutant
resistance to phage SPPI [Pubmed|15576783]
loss of secretion of [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE] [Pubmed|24798022]
The protein
Catalyzed reaction/ biological activity
receptor for phage SPP1 [Pubmed|15576783]
required for depolarization of the cytoplasmic membrane upon binding of phage SPP1 [Pubmed|22154073]
export of [protein|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE] [Pubmed|24828531,23861817]
secretion and delivery of [wiki|LXG domain] toxins [pubmed|34280190]
Protein family
EsaA family (single member, according to UniProt)
Structure
[wiki|Localization]
cell membrane [Pubmed|15576783,23861817], localizes preferentially to the cell poles [Pubmed|21705600]
exposed to the surface [Pubmed|16481324]
cytoplasm (homogeneous) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]-[gene|3CC3E197848E9688413C15CEA7DDCF0A7120A920|yukD]-[gene|3FE4A91C7D0B43C8704391F2F9493852B3AED9B0|essB]-[gene|6007664F3D979B4D8D4662C7F6E5CF2F489268E3|yukB]-[gene|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]-[gene|DA52C4CD130F32734E01A52F2F395127D2260F61|yueC]-[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
description
[Pubmed|22383849]
regulation
expressed in the stationary phase [Pubmed|23861817]
expression is reduced in motile cells as compared to non-motile cells [pubmed|33782055]
regulatory mechanism
[protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]: activation, [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU]-P, [Pubmed|23861817], in [regulon|protein:D343D2096664A972026D911E7A17A35C7B1CD1C9|degU regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|22383849], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab
[gene|50D2A03E2D7B5D461540FD157377E0D37F771888|yukE]→[gene|B258CA26B0EC2310475FCCD67F1F196857FC0004|yueD]
2024-10-01 11:12:47
Jstuelk
110
BB0E1B9684F16E121BAA022EF986B0285FB41FA7
CDC40F8A7006CF56CF9A6155897E8BD27FFEC7AA
Biological materials
Mutant
MGNA-A649 (yueB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/649 NBRP B. subtilis, Japan]
BKE31860 ([gene|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCAAGCTTTTTCGTTGTT, downstream forward: _UP4_TGATCGCAGCATGGAAAAGG
BKK31860 ([gene|0A38B2E900532C9950DE6E629F5EB21D64E18B55|yueB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATCAAGCTTTTTCGTTGTT, downstream forward: _UP4_TGATCGCAGCATGGAAAAGG
References
Reviews
19155186,11973144,38957458 Original Publications
16479537,16481324,15576783,21630458,18487323,17611601,22383849,22171743,21705600,22154073,23861817,24798022,27179995,33584103,33782055,34280190,36154281