frr
168
ribosome recycling factor, catalyzes the dissociation of ribosome subunits following peptide chain release in translation termination
locus
BSU_16520
Molecular weight
20.62 kDa
pI
5.33
function
translation
product
ribosome recycling factor
essential
yes
synonyms
frr
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0233 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,720,526 1,721,083
Phenotypes of a mutant
essential [Pubmed|12682299]
The protein
Catalyzed reaction/ biological activity
catalyzes the dissociation of ribosome subunits following peptide chain release in translation termination [pubmed|11158343]
Protein family
RRF family (single member, according to UniProt)
Structure
[PDB|4GFQ] (from ''B. anthracis'', 75% identity)
[AF|P81101]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|F1969E4C7BAAF70BCBE570F58350C12A3E417539|rpsB]-[gene|94E1130A787CBCCCDBDA93C8AFC24ECB82D5FE61|tsf]-[gene|40655595D0C573B4CB75FB255CBB01A6ACF1F94D|pyrH]-[gene|093960C48AD50C0D0B3A68BBFE7D060BE716935D|frr]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
regulatory mechanism
stringent response: negative regulation, [pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
References
Reviews
Original Publications
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Time of last update: 2024-12-21 00:48:03
Author of last update: Jstuelk