ywiE

ywiE
168

minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress

locus
BSU_37240
Molecular weight
58.08 kDa
pI
8.38
Protein length
Gene length
function
phospholipiid biosynthesis, protection against paraquat stress
product
minor cardiolipin synthetase
essential
no
ec
null
synonyms
ywiE

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1502 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,821,570  3,823,072
The protein
Catalyzed reaction/ biological activity
2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) --> cardiolipin + glycerol (according to UniProt)
Protein family
phospholipase D family (with [protein|B63AAF0D3277FD776944A09D2546F3E48C8716AD|ywjE] and [protein|2079B210322F26EEC3CCF55611622FADDB1D1BC7|clsA], according to UniProt)
[wiki|Domains]
2 PLD phosphodiesterase domains (aa 237-264, aa 413-440) (according to UniProt)
Structure
[AF|P45860]
Paralogous protein(s)
[protein|2079B210322F26EEC3CCF55611622FADDB1D1BC7|clsA], [protein|B63AAF0D3277FD776944A09D2546F3E48C8716AD|ywjE]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|07752EC6940F43DEBD1E9313A2A195E35EDB9F69|ywiE]-[gene|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA]-[gene|685B58AD2A02A0B48B7D4AAAE046DE2CF8F77C58|ywjB]
description
[pubmed|22383849]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|26577401], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|07752EC6940F43DEBD1E9313A2A195E35EDB9F69|ywiE]->[gene|685B58AD2A02A0B48B7D4AAAE046DE2CF8F77C58|ywjB]

2024-09-11 09:15:14

Bzhu

47

212b18f4698de19cc17ce4d25e56c42b2e6ee3aa

1388A2364B0BC385CFA90298AFC1348C8DFABFBB

Biological materials
Mutant
MGNA-A553 (ywiE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/553 NBRP B. subtilis, Japan]
BKE37240 ([gene|07752EC6940F43DEBD1E9313A2A195E35EDB9F69|ywiE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTGATTCTCTCCAATC,  downstream forward: _UP4_TAAGAAAAAAGAAATCTGAT
BKK37240 ([gene|07752EC6940F43DEBD1E9313A2A195E35EDB9F69|ywiE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37240 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTGATTCTCTCCAATC,  downstream forward: _UP4_TAAGAAAAAAGAAATCTGAT
References
14973018,15805528,22582280,16514141

07752EC6940F43DEBD1E9313A2A195E35EDB9F69

Page visits: 5190

Time of last update: 2024-10-09 03:51:07

Author of last update: Melvin.boenninger