ptsA
168
[category|SW.1.2.2|PTS] EIIA component
locus
BSU_22230
Molecular weight
17.79 kDa
pI
5.29
function
uptake and phosphorylation of maltose, N-acetylglucosamine, sucrose, and trehalose
product
[category|SW.1.2.2|PTS] EIIA component
essential
no
synonyms
ptsA, ypqE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2190 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,336,933 2,337,439
The protein
Protein family
[category|SW.1.2.2|PTS] permease, glucose family [Pubmed|10627040]
[wiki|Domains]
[wiki|PTS EIIA domain] type-1 (aa 36-140) (according to UniProt)
Structure
[PDB|1AX3] (IIA domain of [protein|B5E7EB475434E96786C577AE709A21BD702733D8|ptsG], 46% identity) [pubmed|9593197]
[AF|P50829]
Expression and Regulation
Operons
genes
[gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]
description
[Pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [pubmed|30038046], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A477 (ypqE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/477 NBRP B. subtilis, Japan]
QB6099 (aphA3), available in [wiki|Jörg Stülke]'s lab [Pubmed|10627040]
BKE22230 (''ypqE''::''ermC'') (available at the [http://bgsc.org/ BGSC] and in [wiki|Jörg Stülke]'s lab) [pubmed|28189581]
GP1863 (''ypqE''::''ermC'') (available in [wiki|Jörg Stülke]'s lab)
BKE22230 ([gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTATTTTCTCCCTTCT, downstream forward: _UP4_TAAGCAGGGCGTATGCCTTG
BKK22230 ([gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTATTTTCTCCCTTCT, downstream forward: _UP4_TAAGCAGGGCGTATGCCTTG
References
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Time of last update: 2024-10-06 05:56:14
Author of last update: Melvin.boenninger